Collagen, Cosmoderm, Cosmoplast
Aim
Supporting the skin, improving the skin's contour, filling out depressions in the skin due to scars, injury or lines and preventing aging.
There are products from bovine or human derivate collagen:
The injectable bovine collagen is made of sterile, purified collagen from cow skin. The human collagen implants are highly purified and isolated from human skin grown in a laboratory. The cells have been grown for the last ten years or so primarily to manufacture living skin-equivalents to treat burns and ulcers. Most common collagen formulas derived from human dermis include as Cosmoderm® or Cosmoplast®.
ZydermŪ and ZyplastŪ are instead popular brands of injectable bovine collagen.
Procedure
Your doctor will take a complete medical history. Medication that reduce blood clotting, such as aspirin, anti-inflammatory agents, warfarin and some herbal medications, may increase the chance of bleeding. People with severe allergies (anaphylaxis) or allergy to injected local anaesthetics should not be treated with bovine or human collagen. Since injectable bovine collagen is derived from cows it may cause allergic reactions. Approximately 3% of the population is allergic to bovine collagen; these individuals should not receive these implants. Human collagen is a better choice in the following circumstances: • Allergies to foods, especially meat products Family or personal history of severe allergies (including asthma, hay fever and atopic dermatitis)
• Any previous reaction to a test dose of collagen
To see if you are eligible for bovine collagen replacement therapy you will require one or two skin tests. No skin test is necessary for human collagen as allergic reactions are very unlikely.
Collagen treatments are carried out in a medical centre by a specially trained nurse or doctor. The treatment usually take 20 minutes to an hour. After injection, at once the site become tender, red and swollen. This will gradually settle over the next few days. It is safe to cover the treated areas with make-up if you wish. Avoid strenous exercise, sunburn and alcohol during this time. Your therapist may ask to check the results in 2 or 3 weeks and top up with more collagen if necessary.
Duration
Normal activities can be resumed immediatly. Collagen injections are not permanent but collagen slowly breaks down into amino acids that are then absorbed by the body. In most cases, implants last between one to six months, although in some people one implant may be sufficient for up to two years. Repeat treatments will be necessary to maintain the results.
Contra-indications and side effects
• Injections through the skin carry a risk of bacterial infection (impetigo). This is more likely if inflammation is present in the treated area such as acne or rosacea spots. Injections in and around the lips may also provoke cold sores in those prone to them
Allergic reaction to bovine collagen is usually recognized after one or two test doses. In rare cases, allergic reactions may occur during the course of treatment even though there was no reaction to the test dose. They may occur rapidly after treatment or arise weeks to months afterwards. The reaction may clear up in a few days or persist for months. See your doctor immediately if you have an allergic reaction. Allergic reactions may include:
• Shortness of breath, low blood pressure, and chest pain
• Urticaria (hives)
• Red, itchy or sore lumps at injection sites
• Scarring when the lumps have resolved
Products
Cosmoderm and Cosmoplast are the first FDA approved human collagen fillers available. These natural products are for the treatments of wrinkles, scars, acne scars, distrophies and tissue deficiencies, as well as lip enhancement. Unlike other collagen products, Cosmoderm® or Cosmoplast®, do not require pretreatment skin test.
They are injected through a tiny needle, into your on collagen. Since they contain a small amount of local anaesthetic, patients have a minimal discomfort and pain.
• Cosmoderm® or Cosmoplast® are natural, non-allergenic, human collagen
• They have a natural feel
• No need to harvest tissue from other parts of body
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